Advanced hybrid wavetable synthesizer with flexible effects and a built-in sequencer.
VST3supportedAUsupportedAAXsupportedCLAPnot supportedWINsupportedMACsupportedLNXnot supported
Checked September 2026
Serum 2 is best for sound designers wanting deep wavetable synthesis and visual modulation; Omnisphere 3 is best for sound designers and composers wanting a massive, flagship-tier synth library and engine. Serum 2 starts at $249 one-time and Omnisphere 3 at $499 one-time.
Advanced hybrid wavetable synthesizer with flexible effects and a built-in sequencer.

Spectrasonics
Flagship Spectrasonics synthesizer combining multiple synthesis types in one instrument.
| Serum 2 | Omnisphere 3 | |
|---|---|---|
| Best for | sound designers wanting deep wavetable synthesis and visual modulation | sound designers and composers wanting a massive, flagship-tier synth library and engine |
| Starting price | $249 one-time | $499 one-time |
| Free version | No | No |
| Free trial | Yes | — |
| Formats | VST3, AU, AAX | Standalone, VST3, VST2, AU, AAX |
| OS | Windows, macOS | Windows, macOS |
| Key features | Wavetable oscillators, Visual waveform editor, Flexible FX routing, Arpeggiator, Clip sequencer | Hybrid synthesis (sample + granular + FM), Massive built-in sound library, Hardware/software integration, Extensive modulation and effects |
| Developer | Xfer Records | Spectrasonics |