What is the best alternative to Focusrite Scarlett 16i16 (4th Gen)?

Checked September 2026

Best Focusrite Scarlett 16i16 (4th Gen) alternatives (2026)

The closest Focusrite Scarlett 16i16 (4th Gen) alternatives are Focusrite Scarlett Solo (4th Gen), Focusrite Scarlett 2i2 (4th Gen), Focusrite Scarlett 4i4 (4th Gen), based on overlapping categories and operating systems. Focusrite Scarlett 16i16 (4th Gen) is best for home studios expanding with ADAT gear and starts at $409.99.

Focusrite
Focusrite Scarlett Solo (4th Gen)
$159.99once
A 2-in, 2-out USB-C interface with one mic preamp and one dedicated guitar input.
VST3not supportedAUnot supportedAAXnot supportedCLAPnot supportedWINsupportedMACsupportedLNXnot supported
Focusrite
Focusrite Scarlett 2i2 (4th Gen)
$224.99once
A 2-in, 2-out USB-C interface with two mic preamps and Auto Gain.
VST3not supportedAUnot supportedAAXnot supportedCLAPnot supportedWINsupportedMACsupportedLNXnot supported
Focusrite
Focusrite Scarlett 4i4 (4th Gen)
$309.99once
A 4-in, 4-out USB-C interface with MIDI I/O and two mic preamps.
VST3not supportedAUnot supportedAAXnot supportedCLAPnot supportedWINsupportedMACsupportedLNXnot supported
Focusrite
Focusrite Scarlett 18i16 (4th Gen)
$569.99once
An 18-in, 16-out USB-C interface with four remote-controllable mic preamps.
VST3not supportedAUnot supportedAAXnot supportedCLAPnot supportedWINsupportedMACsupportedLNXnot supported
Focusrite
Focusrite Scarlett 18i20 (4th Gen)
$769.99once
An 8-preamp, rackmount USB-C interface with 26 simultaneous inputs and outputs.
VST3not supportedAUnot supportedAAXnot supportedCLAPnot supportedWINsupportedMACsupportedLNXnot supported
Focusrite
Focusrite Clarett+ 2Pre
$559.99once
A 10-in, 4-out USB-C interface with all-analogue Air mode and 8 ADAT inputs.
VST3not supportedAUnot supportedAAXnot supportedCLAPnot supportedWINsupportedMACsupportedLNXnot supported
Universal Audio
Universal Audio Volt 1
PAID
A 1-in, 2-out bus-powered USB interface with a Vintage Mic Preamp mode.
VST3not supportedAUnot supportedAAXnot supportedCLAPnot supportedWINsupportedMACsupportedLNXnot supported+ iOS
Universal Audio
Universal Audio Volt 2
PAID
A 2-in, 2-out bus-powered USB interface with two Vintage Mic Preamp inputs.
VST3not supportedAUnot supportedAAXnot supportedCLAPnot supportedWINsupportedMACsupportedLNXnot supported+ iOS
Universal Audio
Universal Audio Volt 176
PAID
A 1-in, 2-out USB interface with Vintage Mic Preamp mode and a 76 Compressor.
VST3not supportedAUnot supportedAAXnot supportedCLAPnot supportedWINsupportedMACsupportedLNXnot supported+ iOS
Universal Audio
Universal Audio Volt 276
PAID
A 2-in, 2-out USB interface with Vintage Mic Preamp mode and a 76 Compressor.
VST3not supportedAUnot supportedAAXnot supportedCLAPnot supportedWINsupportedMACsupportedLNXnot supported+ iOS

Read the full Focusrite Scarlett 16i16 (4th Gen) review →

Questions people ask

Focusrite Scarlett Solo (4th Gen) is the closest match: it is best for solo creators recording vocals or guitar and starts at $159.99.