A 16-in, 16-out USB-C interface with ADAT, S/PDIF and MIDI.
VST3not supportedAUnot supportedAAXnot supportedCLAPnot supportedWINsupportedMACsupportedLNXnot supported
Checked September 2026
Focusrite Scarlett 16i16 (4th Gen) is best for home studios expanding with ADAT gear; Focusrite Scarlett 18i16 (4th Gen) is best for producers and small bands tracking several sources. Focusrite Scarlett 16i16 (4th Gen) starts at $409.99 and Focusrite Scarlett 18i16 (4th Gen) at $569.99.

A 16-in, 16-out USB-C interface with ADAT, S/PDIF and MIDI.

An 18-in, 16-out USB-C interface with four remote-controllable mic preamps.
| Focusrite Scarlett 16i16 (4th Gen) | Focusrite Scarlett 18i16 (4th Gen) | |
|---|---|---|
| Best for | home studios expanding with ADAT gear | producers and small bands tracking several sources |
| Starting price | $409.99 | $569.99 |
| Free version | No | No |
| Free trial | — | — |
| Formats | USB-C | USB-C |
| OS | Windows, macOS | Windows, macOS |
| Key features | 2 mic/line/instrument preamps, ADAT and S/PDIF in/out, MIDI in/out, 2 headphone outputs, Alt speaker switching, 24-bit/192 kHz | 4 mic/line preamps with 69dB gain range, 2 instrument inputs, ADAT, S/PDIF and MIDI, 2 headphone outputs, 122dB D-A dynamic range, 24-bit/192 kHz |
| Developer | Focusrite | Focusrite |