A 4-in, 4-out USB-C interface with MIDI I/O and two mic preamps.
VST3not supportedAUnot supportedAAXnot supportedCLAPnot supportedWINsupportedMACsupportedLNXnot supported
Checked September 2026
Focusrite Scarlett 4i4 (4th Gen) vs Focusrite Scarlett 16i16 (4th Gen) (2026)
Focusrite Scarlett 4i4 (4th Gen) is best for producers who need MIDI and extra line inputs; Focusrite Scarlett 16i16 (4th Gen) is best for home studios expanding with ADAT gear. Focusrite Scarlett 4i4 (4th Gen) starts at $309.99 and Focusrite Scarlett 16i16 (4th Gen) at $409.99.
A 16-in, 16-out USB-C interface with ADAT, S/PDIF and MIDI.
VST3not supportedAUnot supportedAAXnot supportedCLAPnot supportedWINsupportedMACsupportedLNXnot supported
| Focusrite Scarlett 4i4 (4th Gen) | Focusrite Scarlett 16i16 (4th Gen) | |
|---|---|---|
| Best for | producers who need MIDI and extra line inputs | home studios expanding with ADAT gear |
| Starting price | $309.99 | $409.99 |
| Free version | No | No |
| Free trial | — | — |
| Formats | USB-C | USB-C |
| OS | Windows, macOS | Windows, macOS |
| Key features | 2 mic/line/instrument preamps, 4 line inputs and 4 line outputs, MIDI in and out, Auto Gain and Clip Safe, 24-bit/192 kHz, Focusrite Control 2 | 2 mic/line/instrument preamps, ADAT and S/PDIF in/out, MIDI in/out, 2 headphone outputs, Alt speaker switching, 24-bit/192 kHz |
| Developer | Focusrite | Focusrite |
Questions people ask
Focusrite Scarlett 4i4 (4th Gen) starts at $309.99; Focusrite Scarlett 16i16 (4th Gen) starts at $409.99.
4 line inputs and 4 line outputs, MIDI in and out, Auto Gain and Clip Safe, Focusrite Control 2.
ADAT and S/PDIF in/out, MIDI in/out, 2 headphone outputs, Alt speaker switching.